# Second Cycle — Public Data

## Overview

This archive contains longitudinal data from an N=1 case study documenting a 28-day cyclic hormone protocol following peritoneal flap vaginoplasty. New cycles are added monthly as they complete.

For context on the protocol, methodology, and what this data represents, see [secondcycle.io](https://secondcycle.io).

## Structure

Data is organized by cycle, with each cycle in its own directory:

```
/cycle1/
/cycle2/
...
```

Each cycle directory contains some or all of the following files:

- `cycle{N}_README.md` — narrative overview, protocol summary, deviations, data quality notes
- `cycle{N}_protocol_log.csv` — day-by-day protocol administration
- `cycle{N}_inito.csv` — Inito urinary hormone readings
- `cycle{N}_clue_daily.csv` — symptom and cycle tracking
- `cycle{N}_wearables.csv` — Apple Watch biometrics
- `cycle{N}_serum_labs.csv` — serum lab results (when collected)
- `cycle{N}_evvy_microbiome.csv` / `cycle{N}_evvy_summary.csv` — microbiome results (when collected)
- `cycle{N}_data_dictionary_additions.csv` — variable definitions new to this cycle

Not every file appears in every cycle. Files are only present when data was collected. The cycle-specific README documents what is and is not included.

## Where to Start

For each cycle, start with its README (`cycle{N}_README.md`). It covers what happened that cycle, what data was collected, any protocol deviations, and known data quality issues.

The `data_conventions.md` file in the root of this archive describes project-wide conventions: file naming, schema definitions, formatting rules, and column definitions shared across cycles.

## Baseline Data

Pre-intervention and washout-period data (Phase A) is included in the `baseline/` directory. This covers the period before the cyclic protocol began and establishes reference values.

## License

CC-BY 4.0

## Contact

Questions about this data can be directed to E via the contact methods listed at [secondcycle.io](https://secondcycle.io).